SLC24A5

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SLC24A5 mutation is significantly associated with the total protein of many other genes, with 30 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC24A5-associated genes across cancer lineages are mTOR_pS2448, p27_pT198, and PDCD4. Each is linked with SLC24A5 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC24A5-to-partner and partner-to-SLC24A5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC24A5→partner) and Y-score (partner→SLC24A5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECmTOR_pS2448 →-0.161-2.439.008.01932
UCECp27_pT198 →+0.094+1.807.034.02732
UCECPDCD4 →-0.562-2.321.003.00632
UCECBak →+0.206+1.807.046.02732
LUSCMyosin-IIa_pS1943 →+0.393+2.816.019.03631
UCECEGFR_pY1068 →-0.225-1.807.029.02731
Each partner links to its Q-omics profile. Showing the 6 strongest of 30 associations by consensus.

Exploration