Across TCGA cell cohorts, SLC24A5 mutation is significantly associated with the RNA expression of many other genes, with 77 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC24A5-associated genes across cancer lineages are SRMS, KRT37, and LYZL1. Each is linked with SLC24A5 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC24A5-to-partner and partner-to-SLC24A5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC24A5→partner) and Y-score (partner→SLC24A5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	SRMS →	+0.400	+3.736	<.001	.009	3	2
OVARY	KRT37 →	+0.015	+3.990	<.001	.003	3	1
OVARY	LYZL1 →	+0.033	+3.990	<.001	.003	3	1
OVARY	METTL21C →	+0.038	+3.791	.004	.007	3	1
OVARY	SPATA48 →	+0.008	+4.222	<.001	.006	3	1
OVARY	NPSR1 →	+0.034	+3.772	.007	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 77 associations by consensus.

Exploration

SLC24A5 survival (RNA) · tumor vs normal (RNA) · all SLC24A5 data types