SLC24A4

Across TCGA pan-cancer cohorts, SLC24A4 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of SLC24A4’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where SLC24A4 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SLC24A4 is over-expressed in tumor, although a few such as BLCA and COAD show the opposite, repressed pattern.

KIRC, BLCA, and COAD are the cancer types where SLC24A4 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SLC24A4 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Female	All	+0.333	<.001	11	view →
BLCA	Male	All	−0.145	<.001	11	view →
COAD	Female	All	−0.127	<.001	11	view →
LUAD	Female	II,III,IV	−0.777	<.001	9	view →
LUSC	Female	II,III,IV	−0.897	<.001	8	view →
BRCA	All	II,III,IV	−0.167	<.001	6	view →
KICH	All	All	−0.112	<.001	6	view →
PRAD	All	All	−0.140	<.001	2	view →
READ	Female	All	−0.130	.049	1	view →
HNSC	Female	IV	+0.071	.020	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

SLC24A4–KIRC

Open the KIRC breakdown →