Across TCGA patient cohorts, SLC24A3 mutation is significantly associated with the RNA expression of many other genes, with 4,636 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC24A3-associated genes across cancer lineages are GTSE1, RNA5SP412, and KPNA2. Each is linked with SLC24A3 in more than 3 cancer types. Because this analysis shows association rather than direction, both SLC24A3-to-partner and partner-to-SLC24A3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC24A3→partner) and Y-score (partner→SLC24A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	GTSE1 →	+0.625	+1.721	<.001	<.001	3	4
UCEC	RNA5SP412 →	+0.310	+1.309	.001	.005	3	4
UCEC	KPNA2 →	+0.506	+1.514	<.001	<.001	3	4
UCEC	OIP5 →	+0.607	+1.536	<.001	<.001	3	4
UCEC	PDHX →	+0.450	+1.871	<.001	<.001	3	4
UCEC	VBP1 →	+0.422	+1.584	<.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,636 associations by consensus.

Exploration

SLC24A3 survival (RNA) · tumor vs normal (RNA) · all SLC24A3 data types