Across TCGA patient cohorts, SLC24A3 mutation is significantly associated with the total protein of many other genes, with 48 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC24A3-associated genes across cancer lineages are eIF4E, ACC1, and PCNA. Each is linked with SLC24A3 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC24A3-to-partner and partner-to-SLC24A3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC24A3→partner) and Y-score (partner→SLC24A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eIF4E →	+0.147	+1.807	.009	.003	3	3
UCEC	ACC1 →	+0.255	+1.939	.009	.002	3	3
UCEC	PCNA →	+0.119	+1.201	.042	.025	3	3
UCEC	ASNS →	+0.314	+1.584	.001	.007	3	3
SKCM	mTOR_pS2448 →	-0.153	-2.459	.021	.017	3	2
UCEC	VHL →	-0.602	-1.241	<.001	.012	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 48 associations by consensus.

Exploration

SLC24A3 survival (RNA) · tumor vs normal (RNA) · all SLC24A3 data types