Across TCGA cell cohorts, SLC24A3 mutation is significantly associated with the RNA expression of many other genes, with 229 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC24A3-associated genes across cancer lineages are AVP, USP29, and OR7G2. Each is linked with SLC24A3 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC24A3-to-partner and partner-to-SLC24A3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC24A3→partner) and Y-score (partner→SLC24A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	AVP →	+0.031	+5.209	<.001	.005	3	2
BLOOD_Leukemia	USP29 →	+0.006	+4.922	<.001	.009	3	1
BLOOD_Leukemia	OR7G2 →	+0.032	+5.201	<.001	.006	3	1
BLOOD_Leukemia	OR5M1 →	+0.020	+6.569	<.001	<.001	3	1
LARGE_INTESTINE	EIF3L →	+0.471	+3.067	.009	.009	3	1
LARGE_INTESTINE	RNMT →	+0.586	+3.537	.004	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 229 associations by consensus.

Exploration

SLC24A3 survival (RNA) · tumor vs normal (RNA) · all SLC24A3 data types