SLC23A3

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SLC23A3 mutation is significantly associated with the RNA expression of many other genes, with 956 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC23A3-associated genes across cancer lineages are FOXL3, GTSF1L, and RN7SL185P. Each is linked with SLC23A3 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC23A3-to-partner and partner-to-SLC23A3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC23A3→partner) and Y-score (partner→SLC23A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCAFOXL3 →+0.198+5.098<.001.00132
UCECGTSF1L →+0.291+2.660.006.00532
HNSCRN7SL185P →+0.134+7.954<.001.00832
UCECTRAJ10 →+0.653+2.354<.001.00332
UCECIGHD1-26 →+0.714+3.162<.001.00132
UCECRNU7-188P →+0.298+3.885<.001.00832
Each partner links to its Q-omics profile. Showing the 6 strongest of 956 associations by consensus.

Exploration