Across TCGA patient cohorts, SLC23A3 mutation is significantly associated with the total protein of many other genes, with 29 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC23A3-associated genes across cancer lineages are Caspase-7-cleavedD198, FoxM1, and JNK2. Each is linked with SLC23A3 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC23A3-to-partner and partner-to-SLC23A3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC23A3→partner) and Y-score (partner→SLC23A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Caspase-7-cleavedD198 →	+1.287	+3.189	<.001	.010	3	2
UCEC	FoxM1 →	+0.284	+2.321	.028	.035	3	1
UCEC	JNK2 →	+0.415	+3.009	<.001	.019	3	1
UCEC	Ku80 →	+0.257	+3.179	.030	.010	3	1
UCEC	Lck →	+0.408	+3.459	<.001	.005	3	1
UCEC	Myosin-IIa →	+0.231	+2.818	.013	.035	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 29 associations by consensus.

Exploration

SLC23A3 survival (RNA) · tumor vs normal (RNA) · all SLC23A3 data types