Across TCGA cell cohorts, SLC23A3 mutation is significantly associated with the RNA expression of many other genes, with 15 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC23A3-associated genes across cancer lineages are TPD52L3, H1-6, and WDR87. Each is linked with SLC23A3 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC23A3-to-partner and partner-to-SLC23A3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC23A3→partner) and Y-score (partner→SLC23A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	TPD52L3 →	+0.004	+4.437	<.001	.004	3	1
SKIN	H1-6 →	+0.440	+3.707	<.001	.009	3	1
LARGE_INTESTINE	WDR87 →	+0.016	+2.716	.002	.009	3	1
LARGE_INTESTINE	ZNF454 →	+0.252	+2.921	<.001	.005	3	1
LARGE_INTESTINE	TRDN →	+0.031	+2.791	.001	.005	3	1
LARGE_INTESTINE	GYPE →	+0.014	+3.141	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

Exploration

SLC23A3 survival (RNA) · tumor vs normal (RNA) · all SLC23A3 data types