SLC23A1

Across TCGA cell cohorts, SLC23A1 mutation is significantly associated with the RNA expression of many other genes, with 62 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC23A1-associated genes across cancer lineages are C1QTNF7, PDCL2, and WDR87. Each is linked with SLC23A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC23A1-to-partner and partner-to-SLC23A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C1QTNF7 grouped by SLC23A1-low versus SLC23A1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC23A1→partner) and Y-score (partner→SLC23A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	C1QTNF7 →	+0.106	+3.938	<.001	<.001	3	1
LARGE_INTESTINE	PDCL2 →	+0.212	+3.292	<.001	.006	3	1
LARGE_INTESTINE	WDR87 →	+0.016	+2.716	.002	.009	3	1
BLOOD_Leukemia	GML →	+0.090	+3.567	<.001	.003	3	1
BLOOD_Leukemia	UCP1 →	+0.159	+4.321	.006	.001	3	1
BLOOD_Leukemia	IL2 →	+0.657	+3.691	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 62 associations by consensus.

C1QTNF7 by SLC23A1 expression — LARGE_INTESTINE

Explore this box plot interactively →