SLC22A9

Across TCGA patient cohorts, SLC22A9 mutation is significantly associated with the RNA expression of many other genes, with 3,312 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC22A9-associated genes across cancer lineages are ZWINT, PCAT19, and ADAMTS15. Each is linked with SLC22A9 in more than 3 cancer types. Because this analysis shows association rather than direction, both SLC22A9-to-partner and partner-to-SLC22A9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZWINT grouped by SLC22A9-low versus SLC22A9-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC22A9→partner) and Y-score (partner→SLC22A9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ZWINT →	+0.731	+2.662	<.001	<.001	3	4
UCEC	PCAT19 →	-0.747	-1.882	.001	<.001	3	3
SKCM	ADAMTS15 →	-0.420	-2.434	.006	<.001	3	3
UCEC	IRAG1-AS1 →	-0.418	-3.781	.001	<.001	3	3
SKCM	SLIT3 →	-0.453	-1.690	.009	.002	3	3
SKCM	LINC00092 →	-0.397	-1.469	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,312 associations by consensus.

ZWINT by SLC22A9 expression — UCEC

Explore this box plot interactively →