SLC22A9

Across TCGA patient cohorts, SLC22A9 mutation is significantly associated with the total protein of many other genes, with 22 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC22A9-associated genes across cancer lineages are PCNA, Caspase-8, and eEF2. Each is linked with SLC22A9 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC22A9-to-partner and partner-to-SLC22A9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PCNA grouped by SLC22A9-low versus SLC22A9-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC22A9→partner) and Y-score (partner→SLC22A9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PCNA →	+0.208	+1.765	.003	.013	3	2
UCEC	Caspase-8 →	-0.225	-2.558	.006	<.001	3	2
UCEC	eEF2 →	+0.280	+1.874	.017	.049	3	1
UCEC	eIF4G →	+0.201	+2.459	.049	.018	3	1
UCEC	GAPDH →	+0.399	+1.392	.024	.019	3	1
UCEC	ACC1 →	+0.259	+2.335	.031	.018	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 22 associations by consensus.

PCNA by SLC22A9 expression — UCEC

Explore this box plot interactively →