SLC22A7

Across TCGA cell cohorts, SLC22A7 RNA expression is significantly associated with the go_rna of many other GO terms, with 612 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible SLC22A7-associated GO terms across cancer lineages are Pattern specification process, Negative regulation of purine nucleotide biosynthetic process, and Negative regulation of nucleotide biosynthetic process. Each is linked with SLC22A7 in more than 3 cancer types. Because this analysis shows association rather than direction, both SLC22A7-to-partner and partner-to-SLC22A7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Pattern specification process grouped by SLC22A7-low versus SLC22A7-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC22A7→partner) and Y-score (partner→SLC22A7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Pattern specification process →	-0.025	-0.022	<.001	.009	3	4
LUNG_NSCLC_LUAD	Negative regulation of purine nucleotide biosynthetic process →	+0.098	+0.012	.002	.009	3	4
LUNG_NSCLC_LUAD	Negative regulation of nucleotide biosynthetic process →	+0.098	+0.012	.002	.009	3	4
CNS	Embryonic body morphogenesis →	+0.079	+0.031	<.001	.009	3	4
BONE	Regulation of myoblast fusion →	+0.070	+0.047	.001	.006	3	4
BONE	Regulation of syncytium formation by plasma membrane fusion →	+0.068	+0.047	.001	.006	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 612 associations by consensus.

Pattern specification process by SLC22A7 expression — CNS

Explore this box plot interactively →