Across TCGA patient cohorts, SLC22A5 protein abundance is significantly associated with the RNA expression of many other genes, with 5,744 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SLC22A5-associated genes across cancer lineages are ITGB1, MIR3936HG, and PLEKHO1. Each is linked with SLC22A5 in more than 3 cancer types. Because this analysis shows association rather than direction, both SLC22A5-to-partner and partner-to-SLC22A5 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC22A5→partner) and Y-score (partner→SLC22A5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ITGB1 →	-0.574	-0.472	.003	.005	3	4
BRCA	MIR3936HG →	+1.255	+0.664	<.001	<.001	3	4
UCEC	PLEKHO1 →	-0.588	-0.645	.004	.004	3	4
BRCA	CST3 →	+1.410	+0.589	<.001	<.001	3	3
BRCA	G6PC3 →	+0.975	+0.484	.002	.004	3	3
BRCA	MLKL →	-0.586	-0.428	<.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,744 associations by consensus.

Exploration

SLC22A5 survival (RNA) · tumor vs normal (RNA) · all SLC22A5 data types