SLC22A5

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SLC22A5 mutation is significantly associated with the RNA expression of many other genes, with 1,655 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC22A5-associated genes across cancer lineages are EXOGP1, LACTB, and TIMM44. Each is linked with SLC22A5 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC22A5-to-partner and partner-to-SLC22A5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC22A5→partner) and Y-score (partner→SLC22A5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMEXOGP1 →+0.013+3.990.005.00932
UCECLACTB →+0.501+3.839<.001<.00132
UCECTIMM44 →+0.458+3.202<.001<.00132
UCECGARS1 →+0.543+2.743<.001.00232
UCECGPN3 →+0.464+2.053.008.00532
UCECVPS29 →+0.433+2.716.001.00332
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,655 associations by consensus.

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