Across TCGA patient cohorts, SLC22A4 protein abundance is significantly associated with the RNA expression of many other genes, with 588 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SLC22A4-associated genes across cancer lineages are GNPNAT1, CNIH1, and VRK1. Each is linked with SLC22A4 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC22A4-to-partner and partner-to-SLC22A4 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC22A4→partner) and Y-score (partner→SLC22A4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	GNPNAT1 →	-0.539	-0.660	.001	.002	3	1
GBM	CNIH1 →	-0.541	-0.772	<.001	<.001	3	1
GBM	VRK1 →	-0.637	-0.593	.002	.003	3	1
GBM	SRP54 →	-0.404	-0.636	<.001	<.001	3	1
GBM	PRORP →	-0.436	-0.553	.001	.003	3	1
GBM	SEC23A →	-0.496	-0.754	.006	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 588 associations by consensus.

Exploration

SLC22A4 survival (RNA) · tumor vs normal (RNA) · all SLC22A4 data types