Across TCGA cell cohorts, SLC22A4 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,401 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible SLC22A4-associated GO terms across cancer lineages are Regulation of cell-substrate adhesion, Regulation of cell-matrix adhesion, and Urokinase plasminogen activator signaling pathway. Each is linked with SLC22A4 in more than 14 cancer types. Because this analysis shows association rather than direction, both SLC22A4-to-partner and partner-to-SLC22A4 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC22A4→partner) and Y-score (partner→SLC22A4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of cell-substrate adhesion →	+0.114	+1.057	<.001	<.001	3	15
BONE	Regulation of cell-matrix adhesion →	+0.138	+1.183	<.001	<.001	3	15
LIVER	Urokinase plasminogen activator signaling pathway →	+1.809	+2.649	<.001	<.001	3	15
LUNG_NSCLC_LUSC	Regulation of plasminogen activation →	+0.345	+1.759	<.001	.001	3	14
LUNG_NSCLC_LUSC	Regulation of smooth muscle cell-matrix adhesion →	+1.420	+1.986	<.001	<.001	3	14
LUNG_NSCLC_LUSC	Positive regulation of fibroblast proliferation →	+0.194	+1.585	.001	.003	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,401 associations by consensus.

Exploration

SLC22A4 survival (RNA) · tumor vs normal (RNA) · all SLC22A4 data types