SLC22A31

Across TCGA cell cohorts, SLC22A31 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,676 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC22A31-associated GO terms across cancer lineages are Cytoplasmic translational initiation, Axoneme assembly, and Protein insertion into membrane. Each is linked with SLC22A31 in more than 9 cancer types. Because this analysis shows association rather than direction, both SLC22A31-to-partner and partner-to-SLC22A31 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytoplasmic translational initiation grouped by SLC22A31-low versus SLC22A31-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC22A31→partner) and Y-score (partner→SLC22A31) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Cytoplasmic translational initiation →	+0.070	+3.717	.002	<.001	2	10
UPPER_AERODIGESTIVE_TRACT	Axoneme assembly →	-0.064	-0.548	<.001	.005	3	8
OESOPHAGUS	Protein insertion into membrane →	+0.061	+1.150	.003	.008	3	8
LUNG_NSCLC_LUSC	Granzyme-mediated apoptotic signaling pathway →	+0.051	+0.852	.003	.003	3	7
LIVER	Negative regulation of mRNA metabolic process →	+0.086	+2.627	.003	.002	3	7
SOFT_TISSUE	Protein localization to cytoplasmic stress granule →	+0.088	+0.780	<.001	.002	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,676 associations by consensus.

Cytoplasmic translational initiation by SLC22A31 expression — BLOOD_Myeloma

Explore this box plot interactively →