SLC22A31

Across TCGA cell cohorts, SLC22A31 mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. STOMACH shows the largest number of these associations.

The most reproducible SLC22A31-associated genes across cancer lineages are LHCGR, VAX1, and ADCY8. Each is linked with SLC22A31 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC22A31-to-partner and partner-to-SLC22A31 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LHCGR grouped by SLC22A31-low versus SLC22A31-high in STOMACH.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC22A31→partner) and Y-score (partner→SLC22A31) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	LHCGR →	+0.047	+4.280	<.001	.001	3	1
STOMACH	VAX1 →	+0.431	+4.050	.002	.002	3	1
STOMACH	ADCY8 →	+0.071	+3.830	.003	.005	3	1
STOMACH	DCSTAMP →	+0.190	+3.432	<.001	.008	3	1
STOMACH	TSBP1 →	+0.039	+3.794	.002	.003	3	1
STOMACH	TSGA13 →	+0.021	+3.632	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

LHCGR by SLC22A31 expression — STOMACH

Explore this box plot interactively →