SLC22A3

Across TCGA patient cohorts, SLC22A3 protein abundance is significantly associated with the RNA expression of many other genes, with 5,490 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible SLC22A3-associated genes across cancer lineages are PKD2L1, UCK2, and C16orf89. Each is linked with SLC22A3 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC22A3-to-partner and partner-to-SLC22A3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLC22A3 versus PKD2L1 in CCRCC, with a Pearson correlation of 0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC22A3→partner) and Y-score (partner→SLC22A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	PKD2L1 →	+0.825	+0.369	.007	.006	3	3
OV	UCK2 →	-0.948	-1.208	.006	<.001	3	3
LUAD	C16orf89 →	+1.959	+0.662	<.001	<.001	3	3
OV	CD1C →	+1.115	+0.817	.003	.001	3	3
OV	DHX57 →	-0.734	-0.736	<.001	<.001	3	3
OV	ADRB2 →	+0.997	+0.659	<.001	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,490 associations by consensus.

SLC22A3 vs PKD2L1 — CCRCC

Explore this scatter interactively →