SLC22A3

Across TCGA cell cohorts, SLC22A3 RNA expression is significantly associated with the RNA expression of many other genes, with 5,389 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC22A3-associated genes across cancer lineages are PLG, HKDC1, and PCED1B. Each is linked with SLC22A3 in more than 10 cancer types. Because this analysis shows association rather than direction, both SLC22A3-to-partner and partner-to-SLC22A3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLC22A3 versus PLG in LIVER, with a Pearson correlation of 0.58.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC22A3→partner) and Y-score (partner→SLC22A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	PLG →	+1.834	+3.914	<.001	<.001	2	11
PANCREAS	HKDC1 →	+3.659	+2.614	<.001	<.001	3	7
KIDNEY	PCED1B →	+2.536	+2.337	<.001	<.001	2	7
OESOPHAGUS	PRSS3 →	+3.057	+1.844	<.001	<.001	3	6
PANCREAS	CYP3A5 →	+3.341	+1.860	<.001	<.001	3	6
LIVER	ABCC3 →	+3.806	+3.182	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,389 associations by consensus.

SLC22A3 vs PLG — LIVER

Explore this scatter interactively →