Across TCGA patient cohorts, SLC22A24 mutation is significantly associated with the total protein of many other genes, with 46 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC22A24-associated genes across cancer lineages are PDCD4, EGFR_pY1068, and JNK_pT183_Y185. Each is linked with SLC22A24 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC22A24-to-partner and partner-to-SLC22A24 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC22A24→partner) and Y-score (partner→SLC22A24) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	PDCD4 →	-0.678	-3.000	.001	.035	3	3
UCEC	EGFR_pY1068 →	-0.331	-2.584	<.001	.001	3	2
UCEC	JNK_pT183_Y185 →	-0.210	-2.074	.001	.005	3	2
UCEC	MEK1 →	+0.310	+2.000	.027	.030	3	2
UCEC	STAT3_pY705 →	-0.451	-1.678	<.001	.023	3	2
COAD	ASNS →	+0.908	+3.008	<.001	.019	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 46 associations by consensus.

Exploration

SLC22A24 survival (RNA) · tumor vs normal (RNA) · all SLC22A24 data types