Across TCGA cell cohorts, SLC22A24 mutation is significantly associated with the RNA expression of many other genes, with 13 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible SLC22A24-associated genes across cancer lineages are OR1L3, CLEC1B, and DEFB123. Each is linked with SLC22A24 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC22A24-to-partner and partner-to-SLC22A24 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC22A24→partner) and Y-score (partner→SLC22A24) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	OR1L3 →	+0.014	+4.415	.001	.007	3	1
LUNG_SCLC	CLEC1B →	+0.048	+5.029	<.001	.006	3	1
LUNG_SCLC	DEFB123 →	+0.103	+5.643	<.001	.002	3	1
LUNG_SCLC	KRTAP19-3 →	+0.241	+5.029	<.001	.006	3	1
LUNG_SCLC	OR5M1 →	+0.022	+5.029	<.001	.006	3	1
STOMACH	CT47A6 →	+0.046	+5.285	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

Exploration

SLC22A24 survival (RNA) · tumor vs normal (RNA) · all SLC22A24 data types