SLC22A23

Across TCGA patient cohorts, SLC22A23 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,468 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible SLC22A23-associated proteins across cancer lineages are RASSF4, PIK3AP1, and VAV1. Each is linked with SLC22A23 in more than 4 cancer types. Because this analysis shows association rather than direction, both SLC22A23-to-partner and partner-to-SLC22A23 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLC22A23 versus RASSF4 in HNSC, with a Pearson correlation of -0.29.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC22A23→partner) and Y-score (partner→SLC22A23) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RASSF4 →	-0.453	-0.564	<.001	<.001	3	5
CCRCC	PIK3AP1 →	-0.455	-0.569	<.001	<.001	3	5
CCRCC	VAV1 →	-0.349	-0.302	<.001	.009	3	5
PDAC	PARVG →	-0.383	-0.527	<.001	<.001	3	5
LSCC	WRNIP1 →	+0.430	+0.560	<.001	.002	3	4
BRCA	THEMIS2 →	-0.423	-0.784	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,468 associations by consensus.

SLC22A23 vs RASSF4 — HNSC

Explore this scatter interactively →