SLC22A2

Across TCGA patient cohorts, SLC22A2 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,072 significant associations in total. STAD shows the largest number of these associations.

The most reproducible SLC22A2-associated GO terms across cancer lineages are Endothelium development, Response to transforming growth factor beta, and Response to alcohol. Each is linked with SLC22A2 in more than 15 cancer types. Because this analysis shows association rather than direction, both SLC22A2-to-partner and partner-to-SLC22A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endothelium development grouped by SLC22A2-low versus SLC22A2-high in SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC22A2→partner) and Y-score (partner→SLC22A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	Endothelium development →	+0.098	+0.027	<.001	.002	3	16
STAD	Response to transforming growth factor beta →	+0.093	+0.140	<.001	<.001	3	15
STAD	Response to alcohol →	+0.070	+0.142	<.001	<.001	3	15
STAD	Regulation of actin filament organization →	+0.090	+0.138	<.001	<.001	3	15
STAD	Connective tissue development →	+0.079	+0.170	<.001	<.001	3	14
SCLC	Integrin-mediated signaling pathway →	+0.126	+0.017	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,072 associations by consensus.

Endothelium development by SLC22A2 expression — SCLC

Explore this box plot interactively →