SLC22A2

Across TCGA patient cohorts, SLC22A2 protein abundance is significantly associated with the RNA expression of many other genes, with 1,138 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible SLC22A2-associated genes across cancer lineages are PRODH, LGALS1, and PIK3IP1. Each is linked with SLC22A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC22A2-to-partner and partner-to-SLC22A2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLC22A2 versus PRODH in CCRCC, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC22A2→partner) and Y-score (partner→SLC22A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	PRODH →	+0.998	+0.491	.008	<.001	3	1
CCRCC	LGALS1 →	-0.593	-0.523	.007	.001	3	1
CCRCC	PIK3IP1 →	+0.483	+0.374	<.001	.002	3	1
CCRCC	MIOX →	+1.966	+0.423	.001	.003	3	1
CCRCC	HMOX1 →	+0.576	+0.367	<.001	<.001	3	1
CCRCC	CHADL →	+0.350	+0.426	.002	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,138 associations by consensus.

SLC22A2 vs PRODH — CCRCC

Explore this scatter interactively →