SLC22A2

Across TCGA patient cohorts, SLC22A2 mutation is significantly associated with the RNA expression of many other genes, with 5,956 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC22A2-associated genes across cancer lineages are UTP15, LMTK2, and RPUSD2. Each is linked with SLC22A2 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC22A2-to-partner and partner-to-SLC22A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, UTP15 grouped by SLC22A2-low versus SLC22A2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC22A2→partner) and Y-score (partner→SLC22A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	UTP15 →	+0.514	+2.611	<.001	<.001	3	3
UCEC	LMTK2 →	+0.413	+2.425	.001	.001	3	3
UCEC	RPUSD2 →	+0.304	+3.129	.002	<.001	3	3
UCEC	GATAD2A →	+0.402	+1.968	<.001	<.001	3	3
UCEC	CHAF1A →	+0.736	+2.928	<.001	<.001	3	3
UCEC	HDGFL2 →	+0.312	+3.928	.007	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,956 associations by consensus.

UTP15 by SLC22A2 expression — UCEC

Explore this box plot interactively →