SLC22A18

Across TCGA patient cohorts, SLC22A18 protein abundance is significantly associated with the RNA expression of many other genes, with 11,864 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SLC22A18-associated genes across cancer lineages are CRLF1, EBF3, and STUM. Each is linked with SLC22A18 in more than 4 cancer types. Because this analysis shows association rather than direction, both SLC22A18-to-partner and partner-to-SLC22A18 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLC22A18 versus CRLF1 in LUAD, with a Pearson correlation of -0.26.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC22A18→partner) and Y-score (partner→SLC22A18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	CRLF1 →	-1.344	-0.280	.002	.009	3	5
HNSC	EBF3 →	-0.747	-0.541	<.001	<.001	3	4
GBM	STUM →	-1.003	-0.459	<.001	<.001	3	4
OV	YPEL1 →	-0.546	-0.544	.002	.001	3	4
LSCC	KEL →	-0.535	-0.504	<.001	<.001	3	4
GBM	MPDZ →	-0.602	-0.607	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,864 associations by consensus.

SLC22A18 vs CRLF1 — LUAD

Explore this scatter interactively →