SLC22A17

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SLC22A17 mutation is significantly associated with the RNA expression of many other genes, with 2,251 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC22A17-associated genes across cancer lineages are RNU1-17P, OR51A3P, and RNA5SP109. Each is linked with SLC22A17 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC22A17-to-partner and partner-to-SLC22A17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU1-17P grouped by SLC22A17-low versus SLC22A17-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC22A17→partner) and Y-score (partner→SLC22A17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRNU1-17P →+0.268+2.557<.001.00333
LUSCOR51A3P →+0.375+5.578<.001.00233
COADRNA5SP109 →+0.227+5.149<.001.00133
SKCMCMC4 →+0.024+4.003<.001.00633
LGGRNU1-142P →+0.433+7.977<.001.00732
BRCARNA5SP346 →+0.232+7.731<.001.00932
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,251 associations by consensus.

RNU1-17P by SLC22A17 expression — UCEC

Box plot of RNU1-17P in SLC22A17-low vs SLC22A17-high samples in UCEC.

Explore this box plot interactively →

Exploration