SLC22A17

Across TCGA cell cohorts, SLC22A17 mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible SLC22A17-associated genes across cancer lineages are CCL18, AVP, and DYNAP. Each is linked with SLC22A17 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC22A17-to-partner and partner-to-SLC22A17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCL18 grouped by SLC22A17-low versus SLC22A17-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC22A17→partner) and Y-score (partner→SLC22A17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	CCL18 →	+0.032	+4.212	<.001	.007	3	2
BLOOD_Lymphoma	AVP →	+0.031	+5.209	<.001	.005	3	1
BLOOD_Lymphoma	DYNAP →	+0.071	+4.867	.002	.009	3	1
LUNG_NSCLC_LUAD	CCDC105 →	+0.004	+4.662	<.001	.005	3	1
OVARY	IDI2 →	+0.021	+4.029	.001	.009	3	1
OVARY	ASB17 →	+0.017	+4.807	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

CCL18 by SLC22A17 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →