SLC22A17

Across TCGA cell cohorts, SLC22A17 mutation is significantly associated with the mutation status of many other genes, with 3,047 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC22A17-associated genes across cancer lineages are TSPOAP1, DCAF1, and ANLN. Each is linked with SLC22A17 in more than 4 cancer types. Because this analysis shows association rather than direction, both SLC22A17-to-partner and partner-to-SLC22A17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TSPOAP1 grouped by SLC22A17-low versus SLC22A17-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC22A17→partner) and Y-score (partner→SLC22A17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	TSPOAP1 →	+3.117	+4.491	.004	.004	1	5
LARGE_INTESTINE	DCAF1 →	+3.321	+3.544	<.001	<.001	1	5
OVARY	ANLN →	+4.562	+5.217	<.001	<.001	1	4
OVARY	FOXN3 →	+4.977	+4.415	.007	.007	1	4
STOMACH	ASIC4 →	+4.807	+4.807	.008	.008	1	4
BLOOD_Lymphoma	CRYBG3 →	+4.429	+5.247	.005	.005	1	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,047 associations by consensus.

TSPOAP1 by SLC22A17 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →