SLC22A15

Across TCGA cell cohorts, SLC22A15 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,122 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC22A15-associated GO terms across cancer lineages are Positive regulation of autophagy, Response to endoplasmic reticulum stress, and Response to unfolded protein. Each is linked with SLC22A15 in more than 11 cancer types. Because this analysis shows association rather than direction, both SLC22A15-to-partner and partner-to-SLC22A15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of autophagy grouped by SLC22A15-low versus SLC22A15-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC22A15→partner) and Y-score (partner→SLC22A15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Positive regulation of autophagy →	+0.062	+1.418	.002	<.001	3	12
SOFT_TISSUE	Response to endoplasmic reticulum stress →	+0.061	+1.130	<.001	<.001	3	12
STOMACH	Response to unfolded protein →	+0.097	+1.398	.001	.002	3	12
OVARY	Regulation of intrinsic apoptotic signaling pathway →	+0.072	+1.293	<.001	<.001	3	11
BONE	Cellular response to unfolded protein →	+0.122	+1.952	<.001	<.001	3	11
BONE	Response to topologically incorrect protein →	+0.094	+1.364	<.001	.004	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,122 associations by consensus.

Positive regulation of autophagy by SLC22A15 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →