SLC22A15

Across TCGA cell cohorts, SLC22A15 mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC22A15-associated genes across cancer lineages are NEUROD6, KRTAP4-4, and HTR3D. Each is linked with SLC22A15 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC22A15-to-partner and partner-to-SLC22A15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NEUROD6 grouped by SLC22A15-low versus SLC22A15-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC22A15→partner) and Y-score (partner→SLC22A15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	NEUROD6 →	+0.009	+4.643	<.001	.005	3	1
BLOOD_Lymphoma	KRTAP4-4 →	+0.024	+4.643	<.001	.005	3	1
BLOOD_Lymphoma	HTR3D →	+0.015	+5.247	<.001	.001	3	1
BLOOD_Lymphoma	PRAMEF15 →	+0.079	+4.643	<.001	.005	3	1
LARGE_INTESTINE	MAJIN →	+0.097	+3.554	.002	.007	3	1
LARGE_INTESTINE	OR2T33 →	+0.160	+3.845	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

NEUROD6 by SLC22A15 expression — BLOOD_Lymphoma

Explore this box plot interactively →