SLC22A13

Across TCGA cell cohorts, SLC22A13 mutation is significantly associated with the RNA expression of many other genes, with 25 significant associations in total. CNS shows the largest number of these associations.

The most reproducible SLC22A13-associated genes across cancer lineages are ZPBP, TSPY2, and FAM205A. Each is linked with SLC22A13 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC22A13-to-partner and partner-to-SLC22A13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZPBP grouped by SLC22A13-low versus SLC22A13-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC22A13→partner) and Y-score (partner→SLC22A13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	ZPBP →	+0.159	+4.981	<.001	.008	3	2
LARGE_INTESTINE	TSPY2 →	+0.039	+3.632	<.001	.003	3	1
LARGE_INTESTINE	FAM205A →	+0.028	+3.614	<.001	.006	3	1
CNS	IFNG →	+0.043	+5.321	.003	.005	3	1
CNS	PTH2 →	+0.120	+5.321	<.001	.005	3	1
CNS	ASB10 →	+0.062	+4.981	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

ZPBP by SLC22A13 expression — CNS

Explore this box plot interactively →