Across TCGA cell cohorts, SLC22A12 mutation is significantly associated with the RNA expression of many other genes, with 16 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible SLC22A12-associated genes across cancer lineages are SSMEM1, NTSR2, and ELOA3DP. Each is linked with SLC22A12 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC22A12-to-partner and partner-to-SLC22A12 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC22A12→partner) and Y-score (partner→SLC22A12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	SSMEM1 →	+0.023	+3.707	.008	.009	3	1
LARGE_INTESTINE	NTSR2 →	+0.087	+3.793	<.001	.007	3	1
LARGE_INTESTINE	ELOA3DP →	+0.037	+4.688	<.001	<.001	3	1
LUNG_NSCLC_LUAD	OR1E2 →	+0.026	+5.662	<.001	.002	3	1
LUNG_NSCLC_LUAD	DPRX →	+0.283	+5.228	<.001	.005	3	1
LUNG_NSCLC_LUAD	NANOGNB →	+0.121	+4.887	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

Exploration

SLC22A12 survival (RNA) · tumor vs normal (RNA) · all SLC22A12 data types