SLC22A11

Across TCGA patient cohorts, SLC22A11 protein abundance is significantly associated with the RNA expression of many other genes, with 1,866 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible SLC22A11-associated genes across cancer lineages are KDELR3, TIMP3, and MIOX. Each is linked with SLC22A11 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC22A11-to-partner and partner-to-SLC22A11 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLC22A11 versus KDELR3 in CCRCC, with a Pearson correlation of -0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC22A11→partner) and Y-score (partner→SLC22A11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	KDELR3 →	-1.114	-0.704	<.001	<.001	3	1
CCRCC	TIMP3 →	+0.920	+0.560	.002	<.001	3	1
CCRCC	MIOX →	+3.054	+0.770	<.001	<.001	3	1
CCRCC	PACSIN2 →	+0.345	+0.556	.001	.003	3	1
CCRCC	KIAA0930 →	-0.546	-0.761	<.001	<.001	3	1
CCRCC	KCTD17 →	-0.552	-0.607	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,866 associations by consensus.

SLC22A11 vs KDELR3 — CCRCC

Explore this scatter interactively →