SLC20A2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SLC20A2 mutation is significantly associated with the RNA expression of many other genes, with 3,215 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC20A2-associated genes across cancer lineages are RNA5SP248, CENPU, and ZIC2. Each is linked with SLC20A2 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC20A2-to-partner and partner-to-SLC20A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP248 grouped by SLC20A2-low versus SLC20A2-high in UCS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC20A2→partner) and Y-score (partner→SLC20A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCSRNA5SP248 →+0.395+5.087<.001.00633
UCECCENPU →+0.499+1.562.004.00233
UCECZIC2 →+1.233+1.551<.001.00233
SKCMRNU6-20P →+0.135+3.095<.001.00733
READRNU6-522P →+1.222+6.681<.001<.00132
READMIR6744 →+1.700+5.925<.001.00232
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,215 associations by consensus.

RNA5SP248 by SLC20A2 expression — UCS

Box plot of RNA5SP248 in SLC20A2-low vs SLC20A2-high samples in UCS.

Explore this box plot interactively →

Exploration