SLC20A2

Across TCGA patient cohorts, SLC20A2 mutation is significantly associated with the total protein of many other genes, with 45 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC20A2-associated genes across cancer lineages are 4E-BP1, eEF2, and A-Raf_pS299. Each is linked with SLC20A2 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC20A2-to-partner and partner-to-SLC20A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 4E-BP1 grouped by SLC20A2-low versus SLC20A2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC20A2→partner) and Y-score (partner→SLC20A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	4E-BP1 →	+0.339	+3.906	<.001	<.001	3	3
UCEC	eEF2 →	+0.253	+1.392	.031	.019	3	2
UCEC	A-Raf_pS299 →	-0.139	-3.087	<.001	<.001	3	2
UCEC	TFRC →	+0.501	+1.652	.004	.006	3	2
UCEC	ATM →	-0.480	-2.321	.001	.005	3	2
UCEC	Di-Ras3 →	-0.156	-2.263	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 45 associations by consensus.

4E-BP1 by SLC20A2 expression — UCEC

Explore this box plot interactively →