SLC20A1

Across TCGA patient cohorts, SLC20A1 mutation is significantly associated with the RNA expression of many other genes, with 4,263 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC20A1-associated genes across cancer lineages are HSPD1P12, RN7SKP20, and MAGT1. Each is linked with SLC20A1 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC20A1-to-partner and partner-to-SLC20A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HSPD1P12 grouped by SLC20A1-low versus SLC20A1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC20A1→partner) and Y-score (partner→SLC20A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	HSPD1P12 →	+0.175	+1.741	<.001	.004	3	3
BLCA	RN7SKP20 →	+0.093	+4.618	<.001	<.001	3	2
UCEC	MAGT1 →	+0.494	+2.081	.003	.001	3	2
UCEC	HNRNPL →	+0.361	+2.439	.005	.001	3	2
UCEC	PNPO →	+0.625	+2.070	<.001	.001	3	2
UCEC	PSMD11 →	+0.570	+2.960	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,263 associations by consensus.

HSPD1P12 by SLC20A1 expression — UCEC

Explore this box plot interactively →