SLC20A1

Across TCGA cell cohorts, SLC20A1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,853 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible SLC20A1-associated GO terms across cancer lineages are Regulation of angiotensin-activated signaling pathway, Urokinase plasminogen activator signaling pathway, and Regulation of transforming growth factor beta receptor signaling pathway. Each is linked with SLC20A1 in more than 11 cancer types. Because this analysis shows association rather than direction, both SLC20A1-to-partner and partner-to-SLC20A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of angiotensin-activated signaling pathway grouped by SLC20A1-low versus SLC20A1-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC20A1→partner) and Y-score (partner→SLC20A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Regulation of angiotensin-activated signaling pathway →	+0.120	+1.302	<.001	<.001	3	12
SOFT_TISSUE	Urokinase plasminogen activator signaling pathway →	+0.676	+1.285	.007	<.001	3	11
CNS	Regulation of transforming growth factor beta receptor signaling pathway →	+0.060	+0.745	<.001	.009	3	10
UPPER_AERODIGESTIVE_TRACT	Positive regulation of cell cycle checkpoint →	+0.092	+1.102	<.001	<.001	3	10
OVARY	Positive regulation of fibroblast proliferation →	+0.145	+1.202	<.001	<.001	3	10
BLOOD_Myeloma	Positive regulation of cell cycle process →	+0.069	+0.939	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,853 associations by consensus.

Regulation of angiotensin-activated signaling pathway by SLC20A1 expression — SKIN

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