SLC20A1

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SLC20A1 mutation is significantly associated with the RNA expression of many other genes, with 20 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SLC20A1-associated genes across cancer lineages are ZNF99, OR2V1, and C1orf185. Each is linked with SLC20A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC20A1-to-partner and partner-to-SLC20A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZNF99 grouped by SLC20A1-low versus SLC20A1-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC20A1→partner) and Y-score (partner→SLC20A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LymphomaZNF99 →+0.369+4.867<.001.00932
KIDNEYOR2V1 →+0.029+4.491<.001.00231
KIDNEYC1orf185 →+0.102+4.954<.001<.00131
LARGE_INTESTINEACER1 →+0.074+3.408.003<.00131
LARGE_INTESTINEIQCF6 →+0.168+2.882.001.00531
LARGE_INTESTINEOR12D2 →+0.053+2.882<.001.00531
Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

ZNF99 by SLC20A1 expression — BLOOD_Lymphoma

Box plot of ZNF99 in SLC20A1-low vs SLC20A1-high samples in BLOOD_Lymphoma.

Explore this box plot interactively →

Exploration