SLC1A7

Across TCGA cell cohorts, SLC1A7 RNA expression is significantly associated with the go_rna of many other GO terms, with 679 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible SLC1A7-associated GO terms across cancer lineages are Regulation of synapse organization, Hepatocyte growth factor receptor signaling pathway, and ER-nucleus signaling pathway. Each is linked with SLC1A7 in more than 3 cancer types. Because this analysis shows association rather than direction, both SLC1A7-to-partner and partner-to-SLC1A7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of synapse organization grouped by SLC1A7-low versus SLC1A7-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC1A7→partner) and Y-score (partner→SLC1A7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Regulation of synapse organization →	+0.028	+1.344	.001	.001	3	4
UPPER_AERODIGESTIVE_TRACT	Hepatocyte growth factor receptor signaling pathway →	+0.182	+0.055	<.001	.002	3	3
UPPER_AERODIGESTIVE_TRACT	ER-nucleus signaling pathway →	+0.103	+0.075	<.001	.003	3	3
PANCREAS	Negative regulation of cell cycle checkpoint →	-0.120	-0.387	<.001	.002	3	3
PANCREAS	Negative regulation of response to type II interferon →	+0.128	+0.523	<.001	.006	3	3
PANCREAS	Negative regulation of type II interferon-mediated signaling pathway →	+0.128	+0.523	<.001	.006	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 679 associations by consensus.

Regulation of synapse organization by SLC1A7 expression — LARGE_INTESTINE

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