SLC1A7

Across TCGA cell cohorts, SLC1A7 mutation is significantly associated with the RNA expression of many other genes, with 27 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC1A7-associated genes across cancer lineages are EBF2, TPPP2, and FAM71C. Each is linked with SLC1A7 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC1A7-to-partner and partner-to-SLC1A7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EBF2 grouped by SLC1A7-low versus SLC1A7-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC1A7→partner) and Y-score (partner→SLC1A7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	EBF2 →	+0.304	+3.999	<.001	.005	3	2
SKIN	TPPP2 →	+0.085	+5.217	<.001	<.001	3	1
SKIN	FAM71C →	+0.015	+4.095	.001	.009	3	1
SKIN	GALP →	+0.017	+4.415	<.001	.007	3	1
SKIN	TBC1D3H →	+0.390	+4.095	.001	.009	3	1
STOMACH	OR2AJ1 →	+0.005	+4.285	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 27 associations by consensus.

EBF2 by SLC1A7 expression — BLOOD_Leukemia

Explore this box plot interactively →