SLC1A6

Across TCGA patient cohorts, SLC1A6 mutation is significantly associated with the RNA expression of many other genes, with 1,787 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC1A6-associated genes across cancer lineages are DDX55, CHAC2, and SASS6. Each is linked with SLC1A6 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC1A6-to-partner and partner-to-SLC1A6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DDX55 grouped by SLC1A6-low versus SLC1A6-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC1A6→partner) and Y-score (partner→SLC1A6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	DDX55 →	+0.330	+1.372	.006	.008	3	3
SKCM	CHAC2 →	+0.456	+1.638	.001	<.001	3	3
SKCM	SASS6 →	+0.455	+1.651	.002	<.001	3	3
LIHC	RNU6-805P →	+0.399	+5.174	<.001	.001	3	3
READ	RNA5SP41 →	+0.288	+4.257	<.001	.007	3	3
LGG	RN7SKP192 →	+0.274	+4.529	<.001	.009	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,787 associations by consensus.

DDX55 by SLC1A6 expression — SKCM

Explore this box plot interactively →