SLC1A6

Across TCGA cell cohorts, SLC1A6 RNA expression is significantly associated with the go_rna of many other GO terms, with 473 significant associations in total. URINARY_TRACT shows the largest number of these associations.

The most reproducible SLC1A6-associated GO terms across cancer lineages are Phosphatidylcholine metabolic process, Regulation of Cdc42 protein signal transduction, and Epithelial cell fate commitment. Each is linked with SLC1A6 in more than 3 cancer types. Because this analysis shows association rather than direction, both SLC1A6-to-partner and partner-to-SLC1A6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Phosphatidylcholine metabolic process grouped by SLC1A6-low versus SLC1A6-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC1A6→partner) and Y-score (partner→SLC1A6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Phosphatidylcholine metabolic process →	+0.097	+2.375	.001	<.001	3	4
LUNG_NSCLC_LUSC	Regulation of Cdc42 protein signal transduction →	-0.220	-0.135	<.001	<.001	3	3
LUNG_NSCLC_LUSC	Epithelial cell fate commitment →	-0.248	-0.131	<.001	<.001	3	3
URINARY_TRACT	Regulation of ruffle assembly →	+0.106	+2.680	.003	.009	3	3
URINARY_TRACT	Regulation of type 2 mitophagy →	+0.111	+3.441	.003	.001	3	3
BREAST	Response to endoplasmic reticulum stress →	+0.031	+1.475	.007	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 473 associations by consensus.

Phosphatidylcholine metabolic process by SLC1A6 expression — URINARY_TRACT

Explore this box plot interactively →