SLC1A6

Across TCGA cell cohorts, SLC1A6 mutation is significantly associated with the RNA expression of many other genes, with 50 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC1A6-associated genes across cancer lineages are TMEM95, KDM4E, and C19orf84. Each is linked with SLC1A6 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC1A6-to-partner and partner-to-SLC1A6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TMEM95 grouped by SLC1A6-low versus SLC1A6-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC1A6→partner) and Y-score (partner→SLC1A6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	TMEM95 →	+0.013	+3.684	.003	.004	3	2
BLOOD_Myeloma	KDM4E →	+0.027	+3.285	.001	.009	3	1
BLOOD_Myeloma	C19orf84 →	+0.040	+3.716	<.001	.005	3	1
SKIN	CRYBB1 →	+0.096	+3.793	<.001	.007	3	1
SKIN	TEX43 →	+0.094	+4.217	<.001	.001	3	1
BLOOD_Leukemia	C6orf118 →	+0.051	+3.450	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 50 associations by consensus.

TMEM95 by SLC1A6 expression — BLOOD_Leukemia

Explore this box plot interactively →