SLC1A5

Across TCGA pan-cancer cohorts, SLC1A5 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated SLC1A5 data layer compared with 26 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher SLC1A5 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated SLC1A5 expression acts as an unfavorable survival marker.

CCRCC, HNSC, and PDAC are the cancer types where SLC1A5 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Median	All	0.622	1.000	.002	38	view →
HNSC	OS	Median	All	0.632	0.808	.015	8	view →
PDAC	OS	Median	All	0.472	0.673	.031	5	view →
LSCC	DFS	Median	All	0.495	0.831	.036	4	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

SLC1A5–CCRCC (OS)

Open the CCRCC breakdown →