SLC1A3

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SLC1A3 protein abundance is significantly associated with the RNA expression of many other genes, with 8,132 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SLC1A3-associated genes across cancer lineages are ACP5, TDO2, and PSTPIP2. Each is linked with SLC1A3 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC1A3-to-partner and partner-to-SLC1A3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLC1A3 versus ACP5 in GBM, with a Pearson correlation of -0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC1A3→partner) and Y-score (partner→SLC1A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMACP5 →-0.987-0.455.001.00532
LSCCTDO2 →+0.757+0.934.007.00332
LUADPSTPIP2 →+0.811+0.706<.001.00832
GBMMAGED1 →+0.415+0.528<.001<.00132
LSCCRNY1 →-0.799-0.902.007.00232
LSCCRNU6-696P →-0.568-0.757.002.00232
Each partner links to its Q-omics profile. Showing the 6 strongest of 8,132 associations by consensus.

SLC1A3 vs ACP5 — GBM

Per-sample scatter of SLC1A3 vs ACP5 in GBM (Pearson r = -0.33).

Explore this scatter interactively →

Exploration