SLC1A3

Across TCGA cell cohorts, SLC1A3 mutation is significantly associated with the RNA expression of many other genes, with 36 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC1A3-associated genes across cancer lineages are FAM24A, IL3, and RESP18. Each is linked with SLC1A3 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC1A3-to-partner and partner-to-SLC1A3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FAM24A grouped by SLC1A3-low versus SLC1A3-high in PANCREAS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC1A3→partner) and Y-score (partner→SLC1A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	FAM24A →	+0.083	+5.614	<.001	.002	3	1
CNS	IL3 →	+0.031	+4.981	<.001	.008	3	1
SKIN	RESP18 →	+0.024	+4.415	<.001	.007	3	1
OVARY	IL2 →	+0.028	+5.196	<.001	.005	3	1
OVARY	MTRNR2L10 →	+0.006	+5.196	<.001	.005	3	1
LARGE_INTESTINE	PRAMEF12 →	+0.031	+3.392	.007	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 36 associations by consensus.

FAM24A by SLC1A3 expression — PANCREAS

Explore this box plot interactively →