SLC19A2

Across TCGA patient cohorts, SLC19A2 mutation is significantly associated with the total protein of many other genes, with 22 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC19A2-associated genes across cancer lineages are 14-3-3_beta, A-Raf_pS299, and FoxM1. Each is linked with SLC19A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC19A2-to-partner and partner-to-SLC19A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 14-3-3_beta grouped by SLC19A2-low versus SLC19A2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC19A2→partner) and Y-score (partner→SLC19A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	14-3-3_beta →	-0.125	-3.295	.004	.009	3	1
UCEC	A-Raf_pS299 →	-0.147	-2.321	.004	.034	3	1
UCEC	FoxM1 →	+0.296	+2.999	.008	.035	3	1
UCEC	Acetyl-a-Tubulin-Lys40 →	+0.632	+2.331	.004	.019	3	1
UCEC	JNK_pT183_Y185 →	-0.235	-2.794	.001	.003	3	1
UCEC	JNK2 →	+0.253	+3.026	.003	.018	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 22 associations by consensus.

14-3-3_beta by SLC19A2 expression — UCEC

Explore this box plot interactively →